| Gene Information | |
|---|---|
| Gene Name | OPG |
| Organism | Homo sapiens (Human) |
| Gene Length | 401 |
| Protein Names | Tumor necrosis factor receptor superfamily member 11B (Osteoclastogenesis inhibitory factor) (Osteoprotegerin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O00300 |
| Gene Card | TNFRSF11B |
| Uniprot ID | O00300 |
| Pfam | PF00531; PF00020 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung. |
| Pharmacological Animal Models | 0.175380(Chimpanzee);0.175650(Mouse);0.001000(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3URF (X-ray 2.70A ) |
| DBSNP | rs2073618 rs11573906 rs796051868 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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