| Gene Information | |
|---|---|
| Gene Name | MICAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1957 |
| Protein Names | [F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000133816 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O94851 |
| Gene Card | MICAL2 |
| Uniprot ID | O94851 |
| Pfam | PF12130; PF00307; PF01494; PF00412 |
| In ASD | no |
| Allosteric Prediction | no (-0.999924368) |
| Ortholog in Animals | Alpaca_ MICAL2 ( ortholog_one2one ) Dog_ MICAL2 ( ortholog_one2one ) GuineaPig_ MICAL2 ( ortholog_one2one ) Macaque_ MICAL2 ( ortholog_one2one ) Mouse_ Mical2 ( ortholog_one2one ) Rat_ Mical2 ( ortholog_one2one ) Rabbit_ MICAL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DSP, SPTBN5, ACTN4, DMD, SYNE3, GAS2L2, SPTBN2, FLNB, SPTAN1, SYNE2, PLEC, EPPK1, SYNE1, CLMN, DYTN, MICAL3, PKHD1, SMTNL2, DRP2, UTRN, PKHD1L1, ACTN2, ACTN3, MICAL1, SPTBN1, MACF1, ACTN1, DST, SPTB, GAS2L3, FLNC, FLNA, DTNA, SPTA1, DTNB, SPTBN4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E9K (NMR - ) 5SZH (X-ray 2.30A ) 5SZI (X-ray 2.85A ) 5SZJ (X-ray 2.66A ) 5SZK (X-ray 2.80A ) |
| DBSNP | rs2706656 rs2306727 rs3794084 rs2270515 rs1027335 rs35518829 rs10741578 rs12574273 rs1493953 rs1493954 rs3812753 rs3812754 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:24440334}. Cytoplasm {ECO:0000250|UniProtKB:Q8BML1}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |