| Gene Information | |
|---|---|
| Gene Name | MIC5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1257 |
| Protein Names | Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P32004 |
| Gene Card | L1CAM |
| Uniprot ID | P32004 |
| Pfam | PF13882; PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs201151358 rs796052697 rs137852523 rs137852521 rs28933683 rs137852526 rs137852518 rs1131691900 rs367665974 rs137852524 rs1557092299 rs137852520 rs886039408 rs1064794246 rs782367931 rs782401498 rs137852519 rs398123360 rs1375788131 rs886039409 rs142424573 rs1557091083 rs137852525 rs36021462 rs148516831 rs797045674 rs35902890 rs137852522 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12514225, ECO:0000269|PubMed:20621658, ECO:0000269|PubMed:22973895, ECO:0000269|PubMed:26891472}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q05695}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q05695}. Cell projection, axon {ECO:0000269|PubMed:20621658}. Cell projection, dendrite. Note=Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons (By similarity). In neurons, detected predominantly in axons and cell body, weak localization to dendrites (PubMed:20621658). {ECO:0000250|UniProtKB:Q05695, ECO:0000269|PubMed:20621658}. |
| Mouse PG classification | NA |
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