Gene Information
Gene NameUBC9
OrganismHomo sapiens (Human)
Gene Length158
Protein NamesSUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP63279
Gene CardUBE2I
Uniprot IDP63279
PfamPF00179
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus. {ECO:0000269|PubMed:8610150}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001303(Rat);0.030323(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1A3S  (X-ray  2.80A  1KPS  (X-ray  2.50A  1Z5S  (X-ray  3.01A  2GRN  (X-ray  1.80A  2GRO  (X-ray  1.70A  2GRP  (X-ray  2.05A  2GRQ  (X-ray  1.70A  2GRR  (X-ray  1.30A  2O25  (X-ray  2.60A  2PE6  (X-ray  2.40A  2PX9  (NMR  2XWU  (X-ray  2.80A  3A4S  (X-ray  2.70A  3UIN  (X-ray  2.60A  3UIO  (X-ray  2.60A  3UIP  (X-ray  2.29A  4W5V  (X-ray  2.50A  4Y1L  (X-ray  2.70A  5D2M  (X-ray  2.40A  5F6D  (X-ray  1.55A  5F6E  (X-ray  1.12A  5F6U  (X-ray  1.55A  5F6V  (X-ray  1.49A  5F6W  (X-ray  1.70A  5F6X  (X-ray  1.56A  5F6Y  (X-ray  1.14A  5FQ2  (X-ray  2.20A  6SYF  (X-ray  1.90A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:16631117, ECO:0000269|PubMed:19744555, ECO:0000269|PubMed:22214662, ECO:0000269|PubMed:27068747}. Cytoplasm {ECO:0000269|PubMed:22214662}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12573574}. Note=Mainly nuclear (By similarity). In spermatocytes, localizes in synaptonemal complexes (PubMed:8610150). Recruited by BCL11A into the nuclear body (By similarity). {ECO:0000250|UniProtKB:P63280, ECO:0000269|PubMed:8610150}.
Mouse PG classificationNA
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