| Gene Information | |
|---|---|
| Gene Name | CHRM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Muscarinic acetylcholine receptor M5 |
| Target Name | muscarinic acetylcholine receptor |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184984 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P08912 |
| Gene Card | CHRM5 |
| Uniprot ID | P08912 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.163226468) |
| Ortholog in Animals | Alpaca_ CHRM5 ( ortholog_one2one ) Dog_ CHRM5 ( ortholog_one2one ) GuineaPig_ CHRM5 ( ortholog_one2one ) Macaque_ CHRM5 ( ortholog_one2one ) Mouse_ Chrm5 ( ortholog_one2one ) Pig_ CHRM5 ( ortholog_one2one ) Rat_ Chrm5 ( ortholog_one2one ) Rabbit_ CHRM5 ( ortholog_one2one ) |
| Ohnologs | CHRM3, CHRM1, CHRM2 |
| Paralogs | HRH2, TAAR6, DRD4, HRH1, DRD1, GPR52, HTR1A, HTR1D, CHRM3, CHRM4, HRH3, TAAR5, HTR4, TAAR1, GPR21, CHRM1, HRH4, TAAR9, TAAR8, DRD3, GPR84, CHRM2, GPR161, DRD5, TAAR2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6OL9 (X-ray 2.54A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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