| Gene Information | |
|---|---|
| Gene Name | MGST1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 155 |
| Protein Names | Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I) |
| Target Name | microsomal glutathione s-transferase 1 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000008394 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P10620 |
| Gene Card | MGST1 |
| Uniprot ID | P10620 |
| Pfam | PF01124 |
| In ASD | no |
| Allosteric Prediction | no (-0.316199472) |
| Ortholog in Animals | Alpaca_ MGST1 ( ortholog_one2many ) Dog_ MGST1 ( ortholog_one2one ) GuineaPig_ MGST1 ( ortholog_one2one ) Macaque_ MGST1 ( ortholog_one2one ) Mouse_ Mgst1 ( ortholog_one2one ) Pig_ MGST1 ( ortholog_one2one ) Rat_ Mgst1 ( ortholog_one2one ) Rabbit_ MGST1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PTGES |
| Tissue | NA |
| Tissue Specificity | Highly expressed in liver. {ECO:0000269|PubMed:3372534}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P08011}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:P08011}. |
| Mouse PG classification | NA |
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