| Gene Information | |
|---|---|
| Gene Name | MGCRABGAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 336 |
| Protein Names | TBC1 domain family member 21 (Male germ cell Rab GTPase-activating protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IYX1 |
| Gene Card | TBC1D21 |
| Uniprot ID | Q8IYX1 |
| Pfam | PF00566 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in round and elongated spermatids (at protein level). Expressed specifically in adult testis and very weakly in fetal brain. {ECO:0000269|PubMed:21128978, ECO:0000269|PubMed:33536340}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16958445 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9D9D3}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9D9D3}. Note=Located at the edge of the acrosomal region, neck and annulus during spermiogenesis. Colocalizes with RAB3A at the acrosome-acroplaxome and neck regions of spermatids. Colocalizes with ACTB at the neck region in elongated spermatids. {ECO:0000250|UniProtKB:Q9D9D3}. |
| Mouse PG classification | NA |
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