| Gene Information | |
|---|---|
| Gene Name | MGCA |
| Organism | Homo sapiens (Human) |
| Gene Length | 1429 |
| Protein Names | Attractin (DPPT-L) (Mahogany homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75882 |
| Gene Card | ATRN |
| Uniprot ID | O75882 |
| Pfam | PF00431; PF01344; PF00059; PF01437 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes. {ECO:0000269|PubMed:10811918, ECO:0000269|PubMed:17261078}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6107308 rs17782078 rs3886999 rs12329487 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:7539799}; Single-pass type I membrane protein {ECO:0000269|PubMed:7539799}.; [Isoform 2]: Secreted {ECO:0000269|PubMed:7539799, ECO:0000269|PubMed:9736737}.; [Isoform 3]: Secreted {ECO:0000269|PubMed:7539799}. |
| Mouse PG classification | NA |
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