| Gene Information | |
|---|---|
| Gene Name | G6PC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9) (Glucose-6-phosphatase beta) (G6Pase-beta) (Ubiquitous glucose-6-phosphatase catalytic subunit-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000141349 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BUM1 |
| Gene Card | G6PC3 |
| Uniprot ID | Q9BUM1 |
| Pfam | PF01569 |
| In ASD | no |
| Allosteric Prediction | no (-0.113675302) |
| Ortholog in Animals | Alpaca_ G6PC3 ( ortholog_one2one ) Dog_ G6PC3 ( ortholog_one2one ) GuineaPig_ G6PC3 ( ortholog_one2one ) Macaque_ G6PC3 ( ortholog_one2one ) Mouse_ G6pc3 ( ortholog_one2one ) Pig_ G6PC3 ( ortholog_one2one ) Rat_ G6pc3 ( ortholog_one2one ) Rabbit_ G6PC3 ( ortholog_one2one ) |
| Ohnologs | G6PC2 |
| Paralogs | G6PC1, G6PC2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in skeletal muscle, at intermediate levels in heart, brain, placenta, kidney, colon, thymus, spleen and pancreas. Also detected in testis, prostate, ovary, liver, lung, small intestine and peripheral blood lymphocytes. {ECO:0000269|PubMed:12370122, ECO:0000269|PubMed:12965222, ECO:0000269|PubMed:14765991}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs762019955 rs775224457 rs752966267 rs1373865222 rs267606834 rs766706036 rs1485073209 rs118203969 rs140294222 rs34406052 rs765927570 rs118203968 rs200478425 rs118203971 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:13129915}; Multi-pass membrane protein {ECO:0000269|PubMed:13129915}. |
| Mouse PG classification | NA |
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