| Gene Information | |
|---|---|
| Gene Name | CDNF |
| Organism | Homo sapiens (Human) |
| Gene Length | 187 |
| Protein Names | Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000185267 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q49AH0 |
| Gene Card | CDNF |
| Uniprot ID | Q49AH0 |
| Pfam | PF10208; PF20145 |
| In ASD | no |
| Allosteric Prediction | no (-0.979910963) |
| Ortholog in Animals | Alpaca_ CDNF ( ortholog_one2one ) Dog_ CDNF ( ortholog_one2one ) GuineaPig_ CDNF ( ortholog_one2one ) Macaque_ CDNF ( ortholog_one2one ) Mouse_ Cdnf ( ortholog_one2one ) Rat_ Cdnf ( ortholog_one2one ) Rabbit_ CDNF ( ortholog_one2one ) |
| Ohnologs | MANF |
| Paralogs | MANF |
| Tissue | testis |
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. {ECO:0000269|PubMed:17611540}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LPN (NMR - ) 2W50 (X-ray 1.60A ) 4BIT (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:17611540, ECO:0000269|PubMed:18561914}. |
| Mouse PG classification | NA |
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