Gene Information
Gene NameKIAA0458
OrganismHomo sapiens (Human)
Gene Length1566
Protein NamesArginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9P2R6
Gene CardRERE
Uniprot IDQ9P2R6
PfamPF03154; PF01426; PF01448; PF00320
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Expressed in tumor cell lines. {ECO:0000269|PubMed:10729226, ECO:0000269|PubMed:10814707, ECO:0000269|PubMed:11331249}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2YQK  (NMR 
DBSNP rs765016528  rs766951273  rs878853270  rs869312871 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:10814707, ECO:0000269|PubMed:11331249}. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
Mouse PG classificationNA
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