| Gene Information | |
|---|---|
| Gene Name | CARMIL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1372 |
| Protein Names | Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000186648 ) 3 ( ENSG00000284765 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8ND23 |
| Gene Card | CARMIL3 |
| Uniprot ID | Q8ND23 |
| Pfam | PF17888; PF16000; PF13516 |
| In ASD | no |
| Allosteric Prediction | no (-1.400483399) |
| Ortholog in Animals | Alpaca_ CARMIL3 ( ortholog_one2one ) Dog_ CARMIL3 ( ortholog_one2one ) GuineaPig_ CARMIL3 ( ortholog_one2one ) Macaque_ CARMIL3 ( ortholog_one2one ) Mouse_ Carmil3 ( ortholog_one2one ) Pig_ CARMIL3 ( ortholog_one2one ) Rat_ Carmil3 ( ortholog_one2one ) Rabbit_ CARMIL3 ( ortholog_one2one ) |
| Ohnologs | CARMIL2, CARMIL1 |
| Paralogs | CARMIL1, PPP1R37, RNH1, CARMIL2 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Widely expressed, with much higher levels in fetal tissues than in adult ones. Up-regulated in certain cancer tissues. {ECO:0000269|PubMed:21102520}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10146906 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21102520}. Cell membrane {ECO:0000269|PubMed:26578515}. |
| Mouse PG classification | NA |
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