| Gene Information | |
|---|---|
| Gene Name | MGAT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 741 |
| Protein Names | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000152127 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q09328 |
| Gene Card | MGAT5 |
| Uniprot ID | Q09328 |
| Pfam | PF15027; PF15024 |
| In ASD | no |
| Allosteric Prediction | no (-0.791425837) |
| Ortholog in Animals | Alpaca_ MGAT5 ( ortholog_one2one ) Dog_ MGAT5 ( ortholog_one2one ) GuineaPig_ MGAT5 ( ortholog_one2one ) Macaque_ MGAT5 ( ortholog_one2one ) Mouse_ Mgat5 ( ortholog_one2one ) Pig_ MGAT5 ( ortholog_one2one ) Rat_ Mgat5 ( ortholog_one2one ) Rabbit_ MGAT5 ( ortholog_one2one ) |
| Ohnologs | MGAT5B |
| Paralogs | CCDC126, MGAT5B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ZIB (X-ray 1.90A ) 5ZIC (X-ray 2.10A ) 6YJQ (X-ray 1.90A ) 6YJR (X-ray 2.20A ) 6YJS (X-ray 1.60A ) 6YJT (X-ray 1.70A ) 6YJU (X-ray 1.96A ) 6YJV (X-ray 1.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:P97259}; Single-pass type II membrane protein {ECO:0000269|PubMed:17142794}.; [Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A]: Secreted {ECO:0000269|PubMed:17142794}. |
| Mouse PG classification | NA |
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