| Gene Information | |
|---|---|
| Gene Name | MGAT4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000161013 ) 3 ( ENSG00000284501 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UQ53 |
| Gene Card | MGAT4B |
| Uniprot ID | Q9UQ53 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.151553234) |
| Ortholog in Animals | Alpaca_ MGAT4B ( ortholog_one2one ) Dog_ MGAT4B ( ortholog_one2one ) GuineaPig_ MGAT4B ( ortholog_one2one ) Macaque_ MGAT4B ( ortholog_one2one ) Mouse_ Mgat4b ( ortholog_one2one ) Pig_ MGAT4B ( ortholog_one2one ) Rat_ Mgat4b ( ortholog_one2one ) Rabbit_ MGAT4B ( ortholog_one2one ) |
| Ohnologs | MGAT4A |
| Paralogs | MGAT4A, MGAT4C, MGAT4D |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Strongly overexpressed in pancreatic cancer. {ECO:0000269|PubMed:10372966}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs190631 rs17854722 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9D4R2}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9D4R2}. Note=A processed soluble form also exists. {ECO:0000269|PubMed:17006639}. |
| Mouse PG classification | NA |
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