| Gene Information | |
|---|---|
| Gene Name | MG61 |
| Organism | Homo sapiens (Human) |
| Gene Length | 461 |
| Protein Names | Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.250) (Protein MG61) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H237 |
| Gene Card | PORCN |
| Uniprot ID | Q9H237 |
| Pfam | PF03062 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung. {ECO:0000269|PubMed:12034504}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7URA (EM 3.11A ) 7URC (EM 3.14A ) 7URD (EM 2.92A ) 7URE (EM 3.19A ) |
| DBSNP | rs267606973 rs1602072227 rs1556974235 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9JJJ7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JJJ7}. |
| Mouse PG classification | NA |
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