| Gene Information | |
|---|---|
| Gene Name | MFSD6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 791 |
| Protein Names | Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000151690 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6ZSS7 |
| Gene Card | MFSD6 |
| Uniprot ID | Q6ZSS7 |
| Pfam | PF12832 |
| In ASD | no |
| Allosteric Prediction | no (-1.311040074) |
| Ortholog in Animals | Alpaca_ MFSD6 ( ortholog_one2one ) Dog_ MFSD6 ( ortholog_one2one ) GuineaPig_ MFSD6 ( ortholog_one2one ) Macaque_ MFSD6 ( ortholog_one2one ) Mouse_ Mfsd6 ( ortholog_one2one ) Pig_ MFSD6 ( ortholog_one2one ) Rat_ Mfsd6 ( ortholog_one2one ) Rabbit_ MFSD6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MFSD6L |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expression levels in peripheral blood mononuclear cells are highly variable between individuals, including no expression at all. {ECO:0000269|PubMed:20123006}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9646748 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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