| Gene Information | |
|---|---|
| Gene Name | MFRP |
| Organism | Homo sapiens (Human) |
| Gene Length | 579 |
| Protein Names | Membrane frizzled-related protein (Membrane-type frizzled-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000235718 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BY79 |
| Gene Card | MFRP |
| Uniprot ID | Q9BY79 |
| Pfam | PF00431; PF01392; PF00057 |
| In ASD | no |
| Allosteric Prediction | no (-1.476325066) |
| Ortholog in Animals | Alpaca_ MFRP ( ortholog_one2one ) Dog_ MFRP ( ortholog_one2one ) GuineaPig_ MFRP ( ortholog_one2one ) Macaque_ MFRP ( ortholog_one2one ) Mouse_ Mfrp ( ortholog_one2one ) Pig_ MFRP ( ortholog_one2one ) Rat_ Mfrp ( ortholog_one2one ) Rabbit_ MFRP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CUZD1, CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | medulla.oblongata |
| Tissue Specificity | Specifically expressed in brain. Strongly expressed in medulla oblongata and to a lower extent in hippocampus and corpus callosum. Expressed in keratinocytes. {ECO:0000269|PubMed:11263980, ECO:0000269|PubMed:16442268}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs139436396 rs4639950 rs3814762 rs121908190 rs767183449 rs139725672 rs368172459 rs730882144 rs374823079 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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