Gene Information
Gene NameMFF
OrganismHomo sapiens (Human)
Gene Length342
Protein NamesMitochondrial fission factor
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000168958 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9GZY8
Gene CardMFF
Uniprot IDQ9GZY8
PfamPF05644
In ASDno
Allosteric Predictionno (-1.137409646)
Ortholog in AnimalsAlpaca_ MFF ( ortholog_one2one )
Dog_ MFF ( ortholog_one2one )
GuineaPig_ MFF ( ortholog_one2one )
Macaque_ MFF ( ortholog_one2one )
Mouse_ Mff ( ortholog_one2one )
Pig_ MFF ( ortholog_one2one )
Rat_ Mff ( ortholog_one2one )
Rabbit_ MFF ( ortholog_one2many )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in heart, kidney, liver, brain, muscle, and stomach. {ECO:0000269|PubMed:18353969}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3211097  rs3211098 
Subcellular location [CC]Mitochondrion outer membrane {ECO:0000269|PubMed:18353969, ECO:0000269|PubMed:23921378};
Single-pass type IV membrane protein {ECO:0000255}. Peroxisome {ECO:0000269|PubMed:18353969, ECO:0000269|PubMed:23921378}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q4KM98}.
Mouse PG classificationNA
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