Gene Information
Gene NameNAB2
OrganismHomo sapiens (Human)
Gene Length525
Protein NamesNGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000166886 )
Evolutionary StageEumetazoa
AlphaFoldDBQ15742
Gene CardNAB2
Uniprot IDQ15742
PfamPF04904; PF04905
In ASDno
Allosteric Predictionno (-0.969332735)
Ortholog in AnimalsAlpaca_ NAB2 ( ortholog_one2one )
Dog_ NAB2 ( ortholog_one2one )
GuineaPig_ NAB2 ( ortholog_one2one )
Macaque_ NAB2 ( ortholog_one2one )
Mouse_ Nab2 ( ortholog_one2one )
Pig_ NAB2 ( ortholog_one2one )
Rat_ Nab2 ( ortholog_one2one )
Rabbit_ NAB2 ( ortholog_one2one )
OhnologsNAB1
ParalogsNAB1
TissueNA
Tissue SpecificityWidely expressed at low levels. Highly expressed in melanoma cell lines.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250}. Note=Isoform 2 is not localized to the nucleus. {ECO:0000250}.
Mouse PG classificationNA
click here to return to the previous page