| Gene Information | |
|---|---|
| Gene Name | MBOAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | Ghrelin O-acyltransferase (EC 2.3.1.-) (Membrane-bound O-acyltransferase domain-containing protein 4) (O-acyltransferase domain-containing protein 4) |
| Target Name | ghrelin o acyltransferase |
| Target Type | Patented-recorded target |
| Gene Age | 1488 ( ENSG00000177669 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96T53 |
| Gene Card | MBOAT4 |
| Uniprot ID | Q96T53 |
| Pfam | PF03062 |
| In ASD | no |
| Allosteric Prediction | no (-0.517161503) |
| Ortholog in Animals | Alpaca_ MBOAT4 ( ortholog_one2one ) Dog_ MBOAT4 ( ortholog_one2one ) GuineaPig_ MBOAT4 ( ortholog_one2one ) Macaque_ MBOAT4 ( ortholog_one2one ) Mouse_ Mboat4 ( ortholog_one2one ) Pig_ MBOAT4 ( ortholog_one2one ) Rat_ Mboat4 ( ortholog_one2one ) Rabbit_ MBOAT4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MBOAT1, MBOAT2, PORCN, MBOAT7, LPCAT3 |
| Tissue | ovary |
| Tissue Specificity | Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues. {ECO:0000269|PubMed:18443287}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7813902 rs16876563 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P0C7A3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P0C7A3}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |