| Gene Information | |
|---|---|
| Gene Name | METTL6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 284 |
| Protein Names | tRNA N(3)-methylcytidine methyltransferase METTL6 (EC 2.1.1.-) (Methyltransferase-like protein 6) (hMETTL6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000206562 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TCB7 |
| Gene Card | METTL6 |
| Uniprot ID | Q8TCB7 |
| Pfam | PF08242 |
| In ASD | no |
| Allosteric Prediction | no (-1.147142399) |
| Ortholog in Animals | Alpaca_ METTL6 ( ortholog_one2one ) GuineaPig_ METTL6 ( ortholog_one2one ) Macaque_ METTL6 ( ortholog_one2one ) Mouse_ Mettl6 ( ortholog_one2one ) Pig_ METTL6 ( ortholog_one2one ) Rabbit_ METTL6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | METTL2A, METTL2B, METTL8 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7EZG (X-ray 1.90A ) 7F1E (X-ray 2.59A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:34268557}. Nucleus {ECO:0000269|PubMed:34268557}. |
| Mouse PG classification | NA |
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