Gene Information
Gene NameMETTL18
OrganismHomo sapiens (Human)
Gene Length372
Protein NamesHistidine protein methyltransferase 1 homolog (EC 2.1.1.85) (Arsenic-transactivated protein 2) (AsTP2) (Methyltransferase-like protein 18)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000171806 )
Evolutionary StageEukaryota
AlphaFoldDBO95568
Gene CardMETTL18
Uniprot IDO95568
PfamNA
In ASDno
Allosteric Predictionno (-1.60979045)
Ortholog in AnimalsAlpaca_ METTL18 ( ortholog_one2one )
Dog_ METTL18 ( ortholog_one2one )
GuineaPig_ METTL18 ( ortholog_one2one )
Macaque_ METTL18 ( ortholog_one2one )
Mouse_ Mettl18 ( ortholog_one2one )
Pig_ METTL18 ( ortholog_one2one )
Rat_ Mettl18 ( ortholog_one2one )
Rabbit_ METTL18 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4RFQ  (X-ray  2.40A 
DBSNP rs10489177  rs34396097  rs35984232  rs16862686  rs13375701 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:33693809}. Nucleus {ECO:0000269|PubMed:33693809}. Nucleus, nucleolus {ECO:0000269|PubMed:33693809}.
Mouse PG classificationNA
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