| Gene Information | |
|---|---|
| Gene Name | METAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 386 |
| Protein Names | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) |
| Target Name | methionine aminopeptidase 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164024 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P53582 |
| Gene Card | METAP1 |
| Uniprot ID | P53582 |
| Pfam | PF00557; PF15801 |
| In ASD | no |
| Allosteric Prediction | no (-0.614285086) |
| Ortholog in Animals | Alpaca_ METAP1 ( ortholog_one2one ) Dog_ METAP1 ( ortholog_one2one ) GuineaPig_ METAP1 ( ortholog_one2one ) Macaque_ METAP1 ( ortholog_one2one ) Mouse_ Metap1 ( ortholog_one2one ) Pig_ METAP1 ( ortholog_one2one ) Rat_ Metap1 ( ortholog_one2one ) Rabbit_ METAP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | XPNPEP1, METAP1D, PA2G4, XPNPEP2, METAP2, XPNPEP3, PEPD |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2B3H (X-ray 1.10A ) 2B3K (X-ray 1.55A ) 2B3L (X-ray 1.50A ) 2G6P (X-ray 1.90A ) 2GZ5 (X-ray 1.10A ) 2NQ6 (X-ray 1.50A ) 2NQ7 (X-ray 1.60A ) 4FLI (X-ray 1.55A ) 4FLJ (X-ray 1.74A ) 4FLK (X-ray 1.47A ) 4FLL (X-ray 1.50A ) 4HXX (X-ray 2.09A ) 4IKR (X-ray 1.78A ) 4IKS (X-ray 1.70A ) 4IKT (X-ray 1.60A ) 4IKU (X-ray 1.30A ) 4IU6 (X-ray 1.90A ) 4U1B (X-ray 1.89A ) 4U69 (X-ray 1.60A ) 4U6C (X-ray 1.91A ) 4U6E (X-ray 1.90A ) 4U6J (X-ray 1.56A ) 4U6W (X-ray 1.83A ) 4U6Z (X-ray 1.80A ) 4U70 (X-ray 1.60A ) 4U71 (X-ray 1.80A ) 4U73 (X-ray 1.80A ) 4U75 (X-ray 1.94A ) 4U76 (X-ray 1.87A ) 5YKP (X-ray 1.68A ) 5YR4 (X-ray 1.82A ) 5YR5 (X-ray 1.60A ) 5YR6 (X-ray 1.75A ) 5YR7 (X-ray 2.06A ) 6LZB (X-ray 1.29A ) 6LZC (X-ray 1.35A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}. |
| Mouse PG classification | NA |
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