| Gene Information | |
|---|---|
| Gene Name | MET |
| Organism | Homo sapiens (Human) |
| Gene Length | 1034 |
| Protein Names | SAFB-like transcription modulator (Modulator of estrogen-induced transcription) |
| Target Name | proto-oncogene c-met |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000105976 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NWH9 |
| Gene Card | SLTM |
| Uniprot ID | Q9NWH9 |
| Pfam | PF00076; PF02037 |
| In ASD | no |
| Allosteric Prediction | yes (1.354897132) |
| Ortholog in Animals | Alpaca_ MET ( ortholog_one2one ) Dog_ MET ( ortholog_one2one ) GuineaPig_ MET ( ortholog_one2one ) Macaque_ MET ( ortholog_one2one ) Mouse_ Met ( ortholog_one2one ) Pig_ MET ( ortholog_one2one ) Rat_ Met ( ortholog_one2one ) Rabbit_ MET ( ortholog_one2one ) |
| Ohnologs | MST1R |
| Paralogs | EPHA7, NTRK1, EPHB3, ALK, FGFR3, EPHA2, LMTK2, EPHB1, EPHA3, INSR, PDGFRA, EGFR, CSF1R, ERBB3, KIT, NTRK3, DDR1, ERBB4, EPHA8, TEK, MUSK, MERTK, FGFR4, FLT3, EPHB6, FLT1, DDR2, EPHA6, NTRK2, IGF1R, INSRR, EPHB4, PDGFRB, ERBB2, KDR, EPHA5, FGFR2, TYRO3, MST1R, AXL, EPHB2, ROR1, ROR2, ROS1, EPHA10, EPHA4, RET, LTK, FLT4, TIE1, FGFR1, RYK, EPHA1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7175939 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Note=Detected in punctate structures. {ECO:0000250}. |
| Mouse PG classification | NA |
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