Gene Information
Gene NameCRELD1
OrganismHomo sapiens (Human)
Gene Length420
Protein NamesProtein disulfide isomerase CRELD1 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 1)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000163703 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ96HD1
Gene CardCRELD1
Uniprot IDQ96HD1
PfamPF11938; PF07645
In ASDno
Allosteric Predictionno (-1.073913268)
Ortholog in AnimalsAlpaca_ CRELD1 ( ortholog_one2one )
Dog_ CRELD1 ( ortholog_one2one )
GuineaPig_ CRELD1 ( ortholog_one2one )
Macaque_ CRELD1 ( ortholog_one2one )
Mouse_ Creld1 ( ortholog_one2one )
Pig_ CRELD1 ( ortholog_one2one )
Rat_ Creld1 ( ortholog_one2one )
Rabbit_ CRELD1 ( ortholog_one2one )
OhnologsCRELD2
ParalogsCRELD2, FBLN7, WIF1, DLK2, CD93, CD248, DLL3, CLEC14A
TissueNA
Tissue SpecificityHighly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas. {ECO:0000269|PubMed:12137942}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs279552  rs28941780  rs2302787  rs121912626  rs28942092  rs28942091 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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