| Gene Information | |
|---|---|
| Gene Name | MEPCE |
| Organism | Homo sapiens (Human) |
| Gene Length | 689 |
| Protein Names | 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000146834 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7L2J0 |
| Gene Card | MEPCE |
| Uniprot ID | Q7L2J0 |
| Pfam | PF06859; PF13847 |
| In ASD | no |
| Allosteric Prediction | no (-1.169408249) |
| Ortholog in Animals | Alpaca_ MEPCE ( ortholog_one2many ) Dog_ MEPCE ( ortholog_one2one ) GuineaPig_ MEPCE ( ortholog_one2one ) Macaque_ MEPCE ( ortholog_one2one ) Mouse_ Mepce ( ortholog_one2one ) Pig_ MEPCE ( ortholog_one2one ) Rat_ Mepce ( ortholog_one2one ) Rabbit_ MEPCE ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BCDIN3D |
| Tissue | NA |
| Tissue Specificity | Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis (PubMed:12358911). Weakly or not expressed in other tissues (PubMed:12358911). {ECO:0000269|PubMed:12358911}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001172(Rat);0.003571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5UNA (X-ray 2.55A ) 6DCB (X-ray 2.00A ) 6DCC (X-ray 2.10A ) 7SLP (EM 4.10A ) 7SLQ (EM 3.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19906723}. |
| Mouse PG classification | NA |
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