Gene Information
Gene NameMEP1A
OrganismHomo sapiens (Human)
Gene Length746
Protein NamesMeprin A subunit alpha (EC 3.4.24.18) (Endopeptidase-2) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha)
Target NameNA
Target TypeNA
Gene Age78 ( ENSG00000112818 )
Evolutionary StageEumetazoa
AlphaFoldDBQ16819
Gene CardMEP1A
Uniprot IDQ16819
PfamPF01400; PF00008; PF00629
In ASDno
Allosteric Predictionno (-0.192734544)
Ortholog in AnimalsAlpaca_ MEP1A ( ortholog_one2one )
Macaque_ MEP1A ( ortholog_one2one )
OhnologsNA
ParalogsCNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, NRXN2, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1
Tissueduodenum, small.intestine, colon, small.intestine.Peyers.patch
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2274658  rs12197930  rs2297020  rs2297019  rs1804211 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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