| Gene Information | |
|---|---|
| Gene Name | METTL7B |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Thiol S-methyltransferase METTL7B (Methyltransferase-like protein 7B) (EC 2.1.1.9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000170439 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q6UX53 |
| Gene Card | METTL7B |
| Uniprot ID | Q6UX53 |
| Pfam | PF08241 |
| In ASD | no |
| Allosteric Prediction | no (-1.221014486) |
| Ortholog in Animals | Alpaca_ METTL7B ( ortholog_one2one ) Dog_ METTL7B ( ortholog_one2one ) GuineaPig_ METTL7B ( ortholog_one2one ) Macaque_ METTL7B ( ortholog_one2one ) Mouse_ Mettl7b ( ortholog_one2one ) Pig_ METTL7B ( ortholog_one2one ) Rat_ Mettl7b ( ortholog_one2one ) Rabbit_ METTL7B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AS3MT, METTL27, METTL7A, COQ5 |
| Tissue | epididymis, left.atrium, atrium, liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q562C4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q562C4}. Lipid droplet {ECO:0000250|UniProtKB:Q562C4}. Note=Highly concentrated in the perinuclear area of the endoplasmic reticulum (ER) and surrounding lipid droplets. May be associated with the specific regions of the LR that form lipid droplets and targeted to the initial deposits of lipids where the lipid droplets form. {ECO:0000250|UniProtKB:Q562C4}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |