Gene Information
Gene NameMEK5
OrganismHomo sapiens (Human)
Gene Length448
Protein NamesDual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13163
Gene CardMAP2K5
Uniprot IDQ13163
PfamPF00564; PF00069
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in many adult tissues. Abundant in heart and skeletal muscle.
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);0.001990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2NPT  (X-ray  1.75A  2O2V  (X-ray  1.83A  4IC7  (X-ray  2.60A 
DBSNP rs56241934  rs1226964455  rs55811347 
Subcellular location [CC]NA
Mouse PG classificationNA
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