| Gene Information | |
|---|---|
| Gene Name | MEK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 400 |
| Protein Names | Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P36507 |
| Gene Card | MAP2K2 |
| Uniprot ID | P36507 |
| Pfam | PF00069 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1S9I (X-ray 3.20A ) 4H3Q (X-ray 2.20A ) |
| DBSNP | rs121434497 rs121434498 rs267607230 rs121434499 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10409742}. Membrane {ECO:0000269|PubMed:10409742}; Peripheral membrane protein {ECO:0000269|PubMed:10409742}. Note=Membrane localization is probably regulated by its interaction with KSR1. {ECO:0000269|PubMed:10409742}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |