| Gene Information | |
|---|---|
| Gene Name | MEIS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 477 |
| Protein Names | Homeobox protein Meis2 (Meis1-related protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000134138 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14770 |
| Gene Card | MEIS2 |
| Uniprot ID | O14770 |
| Pfam | PF05920; PF16493 |
| In ASD | no |
| Allosteric Prediction | no (-0.771023549) |
| Ortholog in Animals | Alpaca_ MEIS2 ( ortholog_one2one ) Dog_ MEIS2 ( ortholog_one2one ) GuineaPig_ MEIS2 ( ortholog_one2one ) Macaque_ MEIS2 ( ortholog_one2one ) Mouse_ Meis2 ( ortholog_one2one ) Pig_ MEIS2 ( ortholog_one2one ) Rat_ Meis2 ( ortholog_one2one ) Rabbit_ MEIS2 ( ortholog_one2one ) |
| Ohnologs | MEIS3, MEIS1 |
| Paralogs | PKNOX2, PBX4, MEIS1, PBX3, PBX1, TGIF2LX, TGIF2LY, PKNOX1, TGIF2, PBX2, MEIS3, TGIF1 |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues. Expressed at high level in the lymphoid organs of hematopoietic tissues. Also expressed in some regions of the brain, such as the putamen. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.155893(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3K2A (X-ray 1.95A ) 4XRM (X-ray 1.60A ) 5BNG (X-ray 3.50A ) 5EG0 (X-ray 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P97367}. |
| Mouse PG classification | NA |
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