| Gene Information | |
|---|---|
| Gene Name | ARHGEF10L |
| Organism | Homo sapiens (Human) |
| Gene Length | 1279 |
| Protein Names | Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000074964 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HCE6 |
| Gene Card | ARHGEF10L |
| Uniprot ID | Q9HCE6 |
| Pfam | PF00621 |
| In ASD | no |
| Allosteric Prediction | no (-0.629375618) |
| Ortholog in Animals | Alpaca_ ARHGEF10L ( ortholog_one2one ) Dog_ ARHGEF10L ( ortholog_one2one ) GuineaPig_ ARHGEF10L ( ortholog_one2one ) Macaque_ ARHGEF10L ( ortholog_one2one ) Mouse_ Arhgef10l ( ortholog_one2one ) Pig_ ARHGEF10L ( ortholog_one2one ) Rat_ Arhgef10l ( ortholog_one2one ) Rabbit_ ARHGEF10L ( ortholog_one2one ) |
| Ohnologs | ARHGEF10 |
| Paralogs | ARHGEF10, ARHGEF17 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:16112081}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34417109 rs35497285 rs1421731181 rs6695710 rs2270976 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16112081}. |
| Mouse PG classification | NA |
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