| Gene Information | |
|---|---|
| Gene Name | PLCD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 756 |
| Protein Names | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1) |
| Target Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000187091 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51178 |
| Gene Card | PLCD1 |
| Uniprot ID | P51178 |
| Pfam | PF00168; PF09279; PF00388; PF00387 |
| In ASD | yes |
| Allosteric Prediction | yes (0.632109693) |
| Ortholog in Animals | Alpaca_ PLCD1 ( ortholog_one2one ) Dog_ PLCD1 ( ortholog_one2one ) GuineaPig_ PLCD1 ( ortholog_one2one ) Macaque_ PLCD1 ( ortholog_one2one ) Mouse_ Plcd1 ( ortholog_one2one ) Pig_ PLCD1 ( ortholog_one2one ) Rat_ Plcd1 ( ortholog_one2one ) |
| Ohnologs | PLCD3, PLCD4 |
| Paralogs | PLCG2, PLCD3, PLCB3, PLCE1, PLCG1, PLCB1, PLCD4, PLCB2, PLCB4, PLCL2, PLCH1, PLCL1, PLCZ1, PLCH2 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in lung, liver and heart. Also expressed at least in pancreas, kidney, skeletal muscle, placenta and brain. {ECO:0000269|PubMed:7890667}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs933135 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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