Gene Information
Gene NameMEF
OrganismHomo sapiens (Human)
Gene Length663
Protein NamesETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ99607
Gene CardELF4
Uniprot IDQ99607
PfamPF12310; PF00178
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAbundantly expressed in the placenta and in a variety of myeloid leukemia cell lines. Moderate levels of expression in heart, lung, spleen, thymus, peripheral blood lymphocytes, ovary and colon. Lower levels of expression in Jurkat T-cells and other T-cell lines and no expression in brain. {ECO:0000269|PubMed:8895518, ECO:0000269|PubMed:9524226}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs147410657  rs150084985  rs747352505  rs137884184  rs141440727  rs576980542  rs148953158  rs199975202  rs145786527  rs145281864  rs370055472  rs141284451 
Subcellular location [CC]Nucleus, PML body {ECO:0000269|PubMed:14976184}. Note=Accumulation into PML nuclear bodies is mediated by PML.
Mouse PG classificationNA
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