| Gene Information | |
|---|---|
| Gene Name | S100B |
| Organism | Homo sapiens (Human) |
| Gene Length | 92 |
| Protein Names | Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B) |
| Target Name | protein s100-b |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000160307 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P04271 |
| Gene Card | S100B |
| Uniprot ID | P04271 |
| Pfam | PF00036; PF01023 |
| In ASD | no |
| Allosteric Prediction | no (-0.054399253) |
| Ortholog in Animals | GuineaPig_ S100B ( ortholog_one2one ) Macaque_ S100B ( ortholog_one2one ) Mouse_ S100b ( ortholog_one2one ) Rat_ S100b ( ortholog_one2one ) Rabbit_ S100B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | S100A3, S100A10, S100A4, SNTN, S100A8, S100A13, S100A11, S100A5, S100A14, S100A16, S100Z, S100A1, S100A12, S100P, S100G, S100A2, S100A7, S100A7A, CRNN, S100A9, S100A6 |
| Tissue | NA |
| Tissue Specificity | Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.011940(Mouse);0.002990(Rat);0.053333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MQ1 (NMR - ) 1UWO (NMR - ) 2H61 (X-ray 1.90A ) 2M49 (NMR - ) 2PRU (NMR - ) 3CZT (X-ray 1.40A ) 3D0Y (X-ray 1.50A ) 3D10 (X-ray 1.65A ) 3HCM (X-ray 2.00A ) 4XYN (X-ray 2.55A ) 5CSF (X-ray 2.40A ) 5CSI (X-ray 2.13A ) 5CSJ (X-ray 2.70A ) 5CSN (X-ray 2.95A ) 5D7F (X-ray 1.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9925766}. Nucleus {ECO:0000269|PubMed:9925766}. |
| Mouse PG classification | NA |
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