Gene Information
Gene NameMED8
OrganismHomo sapiens (Human)
Gene Length268
Protein NamesMediator of RNA polymerase II transcription subunit 8 (Activator-recruited cofactor 32 kDa component) (ARC32) (Mediator complex subunit 8)
Target NameNA
Target TypeNA
Gene Age78 ( ENSG00000159479 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96G25
Gene CardMED8
Uniprot IDQ96G25
PfamPF10232
In ASDno
Allosteric Predictionno (-0.82734582)
Ortholog in AnimalsAlpaca_ MED8 ( ortholog_one2one )
Dog_ MED8 ( ortholog_one2many )
GuineaPig_ MED8 ( ortholog_one2one )
Macaque_ MED8 ( ortholog_one2one )
Mouse_ Med8 ( ortholog_one2one )
Pig_ MED8 ( ortholog_one2one )
Rat_ Med8 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.138225(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7EMF  (EM  3.50A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7ENJ  (EM  4.40A  7LBM  (EM  4.80A  7NVR  (EM  4.50A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
click here to return to the previous page