| Gene Information | |
|---|---|
| Gene Name | MED24 |
| Organism | Homo sapiens (Human) |
| Gene Length | 989 |
| Protein Names | Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000008838 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75448 |
| Gene Card | MED24 |
| Uniprot ID | O75448 |
| Pfam | PF11277 |
| In ASD | no |
| Allosteric Prediction | no (-0.624140048) |
| Ortholog in Animals | Alpaca_ MED24 ( ortholog_one2one ) Dog_ MED24 ( ortholog_one2one ) GuineaPig_ MED24 ( ortholog_one2one ) Mouse_ Med24 ( ortholog_one2one ) Pig_ MED24 ( ortholog_one2one ) Rat_ Med24 ( ortholog_one2one ) Rabbit_ MED24 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Abundant in skeletal muscle, heart and placenta. {ECO:0000269|PubMed:9653119}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.094166(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7EMF (EM 3.50A ) 7ENA (EM 4.07A ) 7ENC (EM 4.13A ) 7ENJ (EM 4.40A ) 7LBM (EM 4.80A ) |
| DBSNP | rs34585432 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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