| Gene Information | |
|---|---|
| Gene Name | SMIM20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 67 |
| Protein Names | Small integral membrane protein 20 (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa) (MITRAC7) [Cleaved into: Phoenixin-14 (PNX-14); Phoenixin-20 (PNX-20)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000250317 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N5G0 |
| Gene Card | SMIM20 |
| Uniprot ID | Q8N5G0 |
| Pfam | PF15061 |
| In ASD | no |
| Allosteric Prediction | no (-1.594749582) |
| Ortholog in Animals | Dog_ SMIM20 ( ortholog_one2one ) GuineaPig_ SMIM20 ( ortholog_one2one ) Mouse_ Smim20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level). {ECO:0000269|PubMed:30933929}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4521339 rs2305669 rs6448414 rs2305670 |
| Subcellular location [CC] | [Small integral membrane protein 20]: Mitochondrion inner membrane {ECO:0000269|PubMed:26321642}; Single-pass membrane protein {ECO:0000305}.; [Phoenixin-14]: Secreted {ECO:0000250|UniProtKB:C0HLM6}.; [Phoenixin-20]: Secreted {ECO:0000250|UniProtKB:C0HLM6}. |
| Mouse PG classification | NA |
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