| Gene Information | |
|---|---|
| Gene Name | MED17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 651 |
| Protein Names | Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000042429 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NVC6 |
| Gene Card | MED17 |
| Uniprot ID | Q9NVC6 |
| Pfam | PF10156 |
| In ASD | no |
| Allosteric Prediction | no (-0.980898685) |
| Ortholog in Animals | Alpaca_ MED17 ( ortholog_one2one ) Dog_ MED17 ( ortholog_one2one ) GuineaPig_ MED17 ( ortholog_one2one ) Macaque_ MED17 ( ortholog_one2one ) Mouse_ Med17 ( ortholog_one2one ) Pig_ MED17 ( ortholog_one2one ) Rat_ Med17 ( ortholog_one2one ) Rabbit_ MED17 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10198638}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.094083(Rat);0.140674(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7EMF (EM 3.50A ) 7ENA (EM 4.07A ) 7ENC (EM 4.13A ) 7ENJ (EM 4.40A ) 7LBM (EM 4.80A ) 7NVR (EM 4.50A ) |
| DBSNP | rs2848477 rs35313315 rs267607232 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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