| Gene Information | |
|---|---|
| Gene Name | MED12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2177 |
| Protein Names | Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000184634 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q93074 |
| Gene Card | MED12 |
| Uniprot ID | Q93074 |
| Pfam | PF09497; PF12145; PF12144 |
| In ASD | no |
| Allosteric Prediction | no (-0.647023825) |
| Ortholog in Animals | Alpaca_ MED12 ( ortholog_one2one ) GuineaPig_ MED12 ( ortholog_one2one ) Macaque_ MED12 ( ortholog_one2one ) Mouse_ Med12 ( ortholog_one2one ) Pig_ MED12 ( ortholog_one2one ) Rat_ Med12 ( ortholog_one2one ) Rabbit_ MED12 ( ortholog_one2one ) |
| Ohnologs | MED12L |
| Paralogs | MED12L |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10198638}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.093639(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs80338758 rs80338759 rs387907360 rs387907361 rs1139013 rs387907362 rs879255528 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | LPG |
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