| Gene Information | |
|---|---|
| Gene Name | ME3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 604 |
| Protein Names | NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3) |
| Target Name | nadp-dependent malic enzyme, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000151376 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q16798 |
| Gene Card | ME3 |
| Uniprot ID | Q16798 |
| Pfam | PF00390; PF03949 |
| In ASD | no |
| Allosteric Prediction | yes (0.160586863) |
| Ortholog in Animals | Alpaca_ ME3 ( ortholog_one2one ) Dog_ ME3 ( ortholog_one2one ) GuineaPig_ ME3 ( ortholog_one2one ) Macaque_ ME3 ( ortholog_one2one ) Mouse_ Me3 ( ortholog_one2one ) Pig_ ME3 ( ortholog_one2one ) Rat_ Me3 ( ortholog_one2one ) Rabbit_ ME3 ( ortholog_one2one ) |
| Ohnologs | ME2, ME1 |
| Paralogs | ME1, ME2 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in organs with a low-division rate. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17856661 rs1042780 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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