| Gene Information | |
|---|---|
| Gene Name | TUSC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 110 |
| Protein Names | Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2) |
| Target Name | tumor suppressor candidate 2 |
| Target Type | Clinical trial target |
| Gene Age | 987 ( ENSG00000114383 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75896 |
| Gene Card | TUSC2 |
| Uniprot ID | O75896 |
| Pfam | PF15000 |
| In ASD | no |
| Allosteric Prediction | no (-1.046066618) |
| Ortholog in Animals | Alpaca_ TUSC2 ( ortholog_one2one ) Dog_ TUSC2 ( ortholog_one2one ) GuineaPig_ TUSC2 ( ortholog_one2one ) Macaque_ TUSC2 ( ortholog_one2one ) Mouse_ Tusc2 ( ortholog_one2one ) Rat_ Tusc2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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