| Gene Information | |
|---|---|
| Gene Name | MDP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1239 |
| Protein Names | DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000213920 ) 3 ( ENSG00000285200 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P54098 |
| Gene Card | POLG |
| Uniprot ID | P54098 |
| Pfam | PF00476; PF18136 |
| In ASD | no |
| Allosteric Prediction | no (-1.551118724) |
| Ortholog in Animals | Dog_ MDP1 ( ortholog_one2one ) Pig_ MDP1 ( ortholog_one2one ) Rabbit_ MDP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3IKM (X-ray 3.24A ) 4ZTU (X-ray 3.30A ) 4ZTZ (X-ray 3.44A ) 5C51 (X-ray 3.43A ) 5C52 (X-ray 3.64A ) 5C53 (X-ray 3.57A ) |
| DBSNP | rs121918045 rs3087373 rs3176162 rs121918056 rs113994093 rs113994094 rs61752784 rs121918044 rs745539599 rs2307437 rs150828914 rs113994095 rs145843073 rs121918052 rs121918055 rs61752783 rs2307447 rs781168350 rs774474723 rs556925652 rs113994096 rs375305567 rs121918046 rs796052906 rs2307450 rs121918054 rs113994097 rs769827124 rs41549716 rs113994098 rs121918053 rs121918050 rs763393580 rs139590686 rs121918048 rs11546842 rs113994099 rs121918051 rs768028281 rs121918049 rs201732356 rs368435864 rs1010372555 rs753410045 rs56047213 rs2307442 rs2307441 rs2307440 rs776031396 rs1131691575 rs1085307741 rs3087374 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:18063578}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:18063578}. |
| Mouse PG classification | NA |
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