| Gene Information | |
|---|---|
| Gene Name | MDK |
| Organism | Homo sapiens (Human) |
| Gene Length | 143 |
| Protein Names | Midkine (MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000110492 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P21741 |
| Gene Card | MDK |
| Uniprot ID | P21741 |
| Pfam | PF01091; PF05196 |
| In ASD | no |
| Allosteric Prediction | no (-0.230821473) |
| Ortholog in Animals | Alpaca_ MDK ( ortholog_one2one ) Dog_ MDK ( ortholog_one2many ) GuineaPig_ MDK ( ortholog_one2one ) Macaque_ MDK ( ortholog_one2one ) Mouse_ Mdk ( ortholog_one2one ) Pig_ MDK ( ortholog_one2one ) Rat_ Mdk ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PTN |
| Tissue | NA |
| Tissue Specificity | Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions. {ECO:0000269|PubMed:17379400}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MKC (NMR - ) 1MKN (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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