| Gene Information | |
|---|---|
| Gene Name | MDH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Aromatic alpha-keto acid reductase) (KAR) (EC 1.1.1.96) (Cytosolic malate dehydrogenase) |
| Target Name | malate dehydrogenase, cytoplasmic |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000014641 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P40925 |
| Gene Card | MDH1 |
| Uniprot ID | P40925 |
| Pfam | PF02866; PF00056 |
| In ASD | no |
| Allosteric Prediction | yes (1.040657074) |
| Ortholog in Animals | Alpaca_ MDH1 ( ortholog_one2one ) Dog_ MDH1 ( ortholog_one2one ) GuineaPig_ MDH1 ( ortholog_one2one ) Macaque_ MDH1 ( ortholog_one2one ) Mouse_ Mdh1 ( ortholog_one2one ) Pig_ MDH1 ( ortholog_one2one ) Rat_ Mdh1 ( ortholog_one2one ) Rabbit_ MDH1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MDH1B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7RM9 (X-ray 1.65A ) 7RRL (X-ray 2.05A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
| click here to return to the previous page | |