| Gene Information | |
|---|---|
| Gene Name | MDDX28 |
| Organism | Homo sapiens (Human) |
| Gene Length | 540 |
| Protein Names | Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NUL7 |
| Gene Card | DDX28 |
| Uniprot ID | Q9NUL7 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate. {ECO:0000269|PubMed:11350955}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001516(Rat);0.03(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OI6 (EM 5.70A ) |
| DBSNP | rs237831 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11350955, ECO:0000269|PubMed:25683708}. Mitochondrion {ECO:0000269|PubMed:11350955}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:25683715}. Mitochondrion matrix {ECO:0000269|PubMed:25683708}. Note=Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000269|PubMed:25683708, ECO:0000269|PubMed:25683715}. |
| Mouse PG classification | NA |
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