| Gene Information | |
|---|---|
| Gene Name | MCTS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 181 |
| Protein Names | Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000232119 ) 3 ( ENSG00000288295 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9ULC4 |
| Gene Card | MCTS1 |
| Uniprot ID | Q9ULC4 |
| Pfam | PF17832; PF01472 |
| In ASD | no |
| Allosteric Prediction | no (-1.264353556) |
| Ortholog in Animals | Alpaca_ MCTS1 ( ortholog_one2one ) Dog_ MCTS1 ( ortholog_one2many ) GuineaPig_ MCTS1 ( ortholog_one2one ) Macaque_ MCTS1 ( ortholog_one2one ) Mouse_ Mcts1 ( ortholog_one2one ) Rat_ Mcts1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MCTS2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Over-expressed in T-cell lymphoid cell lines and in non-Hodgkin lymphoma cell lines as well as in a subset of primary large B-cell lymphomas. {ECO:0000269|PubMed:9766643}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.021053(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3R90 (X-ray 1.70A ) 5ONS (X-ray 2.14A ) 5VYC (X-ray 6.00A ) 6MS4 (X-ray 2.00A ) |
| DBSNP | rs2233110 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11709712, ECO:0000269|PubMed:16982740}. Note=Nuclear relocalization after DNA damage. |
| Mouse PG classification | NA |
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