| Gene Information | |
|---|---|
| Gene Name | MCT12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 516 |
| Protein Names | Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZSM3 |
| Gene Card | SLC16A12 |
| Uniprot ID | Q6ZSM3 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Most highly expressed in kidney, followed by retina, lung, heart and testis. Very weakly expressed in brain and liver. Also detected in lens. {ECO:0000269|PubMed:18304496, ECO:0000269|PubMed:23578822}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs759863805 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:21778275, ECO:0000269|PubMed:23578822, ECO:0000269|PubMed:31784090, ECO:0000269|PubMed:32249133}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8BGC3}; Multi-pass membrane protein {ECO:0000255}. Note=Interaction with isoform 2 of BSG is required for its localization to the plasma membrane. {ECO:0000269|PubMed:26376857}. |
| Mouse PG classification | NA |
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