| Gene Information | |
|---|---|
| Gene Name | ESRRA |
| Organism | Homo sapiens (Human) |
| Gene Length | 423 |
| Protein Names | Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1) |
| Target Name | steroid hormone receptor err1 |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000173153 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P11474 |
| Gene Card | ESRRA |
| Uniprot ID | P11474 |
| Pfam | PF00104; PF00105 |
| In ASD | yes |
| Allosteric Prediction | yes (0.986210551) |
| Ortholog in Animals | Alpaca_ ESRRA ( ortholog_one2one ) Dog_ ESRRA ( ortholog_one2one ) GuineaPig_ ESRRA ( ortholog_one2one ) Macaque_ ESRRA ( ortholog_one2one ) Mouse_ Esrra ( ortholog_one2one ) Pig_ ESRRA ( ortholog_one2one ) Rat_ Esrra ( ortholog_one2one ) |
| Ohnologs | ESRRB, ESR2, PGR, ESR1, ESRRG |
| Paralogs | ESRRG, ESRRB, NR3C1, ESR1, AR, ESR2, PGR, NR3C2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1XB7 (X-ray 2.50A ) 2PJL (X-ray 2.30A ) 3D24 (X-ray 2.11A ) 3K6P (X-ray 2.00A ) 7E2E (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:18063693, ECO:0000269|PubMed:21190936}. Cytoplasm {ECO:0000269|PubMed:21190936}. Note=Co-localizes to the cytoplasm only in presence of MAPK15. {ECO:0000269|PubMed:21190936}. |
| Mouse PG classification | NA |
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