| Gene Information | |
|---|---|
| Gene Name | IRF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 503 |
| Protein Names | Interferon regulatory factor 7 (IRF-7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000185507 ) 3 ( ENSG00000276561 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q92985 |
| Gene Card | IRF7 |
| Uniprot ID | Q92985 |
| Pfam | PF00605; PF10401 |
| In ASD | no |
| Allosteric Prediction | no (-0.102288934) |
| Ortholog in Animals | Alpaca_ IRF7 ( ortholog_one2one ) GuineaPig_ IRF7 ( ortholog_one2one ) Macaque_ IRF7 ( ortholog_one2one ) Mouse_ Irf7 ( ortholog_one2one ) Pig_ IRF7 ( ortholog_one2one ) Rat_ Irf7 ( ortholog_one2one ) Rabbit_ IRF7 ( ortholog_one2one ) |
| Ohnologs | IRF3 |
| Paralogs | IRF4, IRF5, IRF3, IRF6, IRF9, IRF2, IRF8, IRF1 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in spleen, thymus and peripheral blood leukocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2O61 (X-ray 2.80A ) |
| DBSNP | rs1061502 rs41313489 rs786205223 rs1131665 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Note=The phosphorylated and active form accumulates selectively in the nucleus. |
| Mouse PG classification | NA |
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