| Gene Information | |
|---|---|
| Gene Name | MCM9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1143 |
| Protein Names | DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000111877 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NXL9 |
| Gene Card | MCM9 |
| Uniprot ID | Q9NXL9 |
| Pfam | PF00493; PF17855; PF17207 |
| In ASD | no |
| Allosteric Prediction | no (-0.947213282) |
| Ortholog in Animals | Alpaca_ MCM9 ( ortholog_one2one ) Dog_ MCM9 ( ortholog_one2one ) GuineaPig_ MCM9 ( ortholog_one2one ) Macaque_ MCM9 ( ortholog_one2one ) Mouse_ Mcm9 ( ortholog_one2one ) Rabbit_ MCM9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MCMDC2, MCM4, MCM8, MCM2, MCM5, MCM6, MCM7, MCM3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.168454(Rat);0.127889(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7DPD (X-ray 2.55A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23401855, ECO:0000269|PubMed:26300262}. Chromosome {ECO:0000269|PubMed:23401855, ECO:0000269|PubMed:26300262}. Note=Colocalizes to nuclear foci with RPA1 following DNA damage (PubMed:23401855). Localizes to double-stranded DNA breaks (PubMed:23401855). Recruited to chromatin by MSH2 (PubMed:26300262). {ECO:0000269|PubMed:23401855, ECO:0000269|PubMed:26300262}. |
| Mouse PG classification | LPG |
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